Background
Traditional clinical practice guideline (CPG) development often lacks direct and holistic patient input, potentially leading to biased priorities and limited patient-centeredness. Short-video platforms, such as TikTok and Douyin, are increasingly generating user-generated health-related content, offering a unique opportunity to capture real-world patient experiences and provide new insights for CPG development.

Objective:
This study aims to explore the feasibility and outline a framework for integrating patient-generated short-video content into CPG development to enhance patient-centered recommendations.

Methods
A preliminary survey of short-video content related to health experiences was conducted in TikTok and Douyin to assess the availability and relevance of patient’s perspectives. A literature review and expert consultations were conducted to identify key steps for integrating patient narratives from short-video platforms into CPG development.

Results
Short-video content offers rich insights into patient experiences, particularly regarding treatment preferences, unmet needs, quality of life, and real-world challenges. The proposed framework consists of five practical steps: (1) establishing strict selection criteria for identifying relevant short-video content from real patients, (2) conducting qualitative analysis to extract key themes, (3) aligning thematic findings with clinical evidence, (4) engaging patients and stakeholders for validation and prioritization, and (5) addressing ethical and practical considerations, including privacy, informed consent, and cultural sensitivity. These steps enable the integration of real-world patient experiences into guideline development, enhancing their relevance and applicability.

Discussion
Incorporating patient-generated short-video content into CPG development is a novel and promising approach to ensure the meaningful involvement of patient voices, promoting more patient-centered and contextually relevant clinical recommendations.

Background:
The evidence-based (EB) social care guidelines are pivotal in ensuring scientific integrity,relevance,and practical utility,which are essential for improving the effectiveness and efficiency of social care services.Social care guidelines are crucial in bridging the gap between research and practice.

Methods:
The Campbell China Network initiated the Guidance Research for Evidence-Based Guidelines for Social Care (EBGSC).The methods primarily employed in the development of the guidance protocol encompass systematic review,consensus methods,the Delphi technique,and expert opinion.The system searches academic databases to extract key guideline - development elements.Then,a 20-expert group in social care and EB methodology will be convened to discuss and supplement the method's professional specificity via online meetings,formulating initial guideline items.Finally,the Delphi method,after two feedback rounds,constructed a method item for EBGSC development,which was then piloted for external review before the method interpretation was completed.

Results:
After retrieval and screening,a total of 10 EB guideline development methods applicable to the field of social care were obtained in this study,and 9 key steps were identified as necessary elements for constructing EBGSC.Methodological improvements were suggested.After a Delphi survey with 19 experts (Kendall coefficient rising from 0.415 to 0.559),the method was finalized.It includes three stages:Evidence evaluation and grading stage (systematic retrieval of evidence,evidence evaluation and synthesis,evidence grading);The development,release,and update phase (developing recommendations for guidelines,writing and publishing guidelines,and updating guidelines).

Discussion:
This study lays the foundation for developing methodologies for EB guideline creation in social care. It aims to promote scientific rigor and transparency in social care practices, ultimately improving the overall quality of social care services.

workshop
Background
Universally acknowledged standards for trustworthy guidelines include the necessity to ground recommendations in patient values and preferences. Sources of information regarding the relative importance patients place in outcomes include cross-sectional surveys that may be unavailable or limited by risk of bias, inconsistency, imprecision, and indirectness; patient partners on guideline panels; focus group commissioned by guideline panels; or experience in shared decision making. Unstructured discussions of guideline panelists’ views regarding target patient values and preferences are often challenging, suggesting the need for more structured approach.
Objectives
This workshop will introduce and discuss a novel panel survey approach that guideline panels have successfully applied and have proved useful in helping panels explicitly consider and incorporate patient values and preferences in making recommendations.
Description
The workshop comprises four sections, combing short presentation with large and small group discussions. (1) A short presentation will introduce the key concepts in the panel survey approach. [1] (2) Using a worked example, workshop leads will introduce three objectives of the panel survey approach and participants will discuss how to design a panel survey eliciting guideline panels’ inferences on patient values and preference. (3) In the following small group discussions, participants will, given case scenarios, work together to create panel surveys corresponding to each of the three objectives. (4) In the final feedback and summary, participants will reflect on their experience of designing surveys, and workshop leads will summarize some take home messages.

Assessing the Impact of RIGHT on Guideline Quality: A Systematic Review

Background: RIGHT, published in 2016, aims to improve the reporting quality of healthcare guidelines. It addresses the limitations of existing tools, such as poor quality and outdated information. The RIGHT checklist provides 22 essential items to help guideline developers, editors, peer reviewers, and practitioners present clear, transparent, and consistent information.

Objective: This study aimed to systematically review the reporting quality of clinical practice guidelines (CPGs) before and after the publication of RIGHT.

Methods:
We conducted a comprehensive search in multiple databases: G-I-N, MEDLINE, Embase and Web of Science. We included CPGs developed in English between 2008 and 2024. Given the large sample size, we sampled based on publication years, with the sampling proportion determined by the final number of guidelines retrieved. The RIGHT checklist was used to appraise the reporting quality of the included guidelines.
We focused on two key dimensions：1.Usage of the RIGHT checklist: We assessed whether guidelines followed the 22 items of the RIGHT checklist. 2.Methodology quality assessment tools: We examined whether the guidelines used other established quality assessment tools like AGREE II, and how they were applied.

Results:
Findings are under analysis and will be presented at the upcoming conference.

Conclusion:
The study will provide valuable insights into the impact of the RIGHT checklist on the reporting quality of clinical practice guidelines. It will help explore its impact on clarity, transparency, and consistency of CPGs. The findings will offer useful information for healthcare practitioners and policymakers.

Background :
Vulnerable people mistreatment is a widespread and serious problem in social and care institutional settings. HAS was mandated by health minister to produce national guidelines and implementation tools. They allow a better knowledge of the causes of abuse and contributing factors in order to develop effective solutions.

Method :
A scoping phase to identify major questions, barriers and levers, and key issues through a literature analysis and consultation of both experts and stakeholders, patient associations.The second phase included a workgroup including 30% of patient representative. A testing phase to facilitate recommendations implementation. Then a stakeholder review.

Results :
HAS proposes guidelines, implementation tools, and patient and caregiver leaflets. Seven priorities are proposed to prevent abuse :
• governance and management involvement,
• patient and caregivers involvement,
• three analysis levels are necessary to identify risk factors and preventive actions plan : organisational aspects, teamwork and patient vulnerability.
• individualized plan has to be regularly reviewed involving patients and caregivers,
• patient relatives have to be a strong partnership to propose solutions
• respectful professional attitudes and a reporting culture
• collaboration between patient representative and professionals
Practical tools are needed to engage discussion between teams and patient to prevent abuse.

Discussion:
This work highlights the need for providers, patients and caregivers to be aware of any potential signs of abuse.This systemic and combined approach (guidelines and tools) is to be taken into account by the French accreditation of healthcare organizations and social evaluations process.

Planetary health, which focuses on the interdependence between human health and the natural systems of the Earth, requires robust, scalable, and adaptive frameworks to address complex global challenges. Achieving better planetary health demands innovative approaches to develop and implement guidelines that integrate health considerations into all policies, spanning sectors such as agriculture, urban planning, energy, and education.This presentation explores cutting-edge methodologies to create and scale guidelines that address the critical intersections of human and environmental health. It highlights the use of technological advancements such as artificial intelligence, big data analytics, and digital platforms to analyze, design, and disseminate evidence-based policies. By leveraging interdisciplinary partnerships, these approaches enable the co-creation of guidelines that are culturally relevant, geographically adaptable, and economically feasible.Case studies from successful initiatives illustrate the integration of planetary health principles into policy frameworks. Examples include the use of real-time climate and health data to inform urban air quality regulations, the implementation of sustainable food systems to mitigate both malnutrition and environmental degradation, and community-driven projects that align health and conservation efforts.A special focus is placed on strategies for scaling these guidelines, including stakeholder engagement, capacity building, and leveraging global networks to share best practices. Collaborative partnerships across governments, the private sector, academia, and civil society are identified as key to fostering innovation and ensuring sustainable implementation at scale.This session will demonstrate that by prioritizing innovative approaches and inclusive partnerships, we can develop actionable guidelines that not only improve human health outcomes but also safeguard the planet for future generations.

Background
Developers of Clinical Practice Guidelines (CPGs) are encouraging the engagement of various interest-holders in the entire process of CPG development and facilitating the dissemination, implementation, and application of these guidelines. The number of CPGs in the field of Traditional, Complementary, and Integrative (TCI) medicine is gradually increasing, but the extent to which and how interest-holders are engaged remains unclear.

Objective
Aims to review the current status and gaps in interest-holder engagement in TCI CPGs.

Methods
We conducted this scoping review following the PRISMA-ScR Checklist. A systematic search of scientific literature published before January 2025 was conducted to select TCI CPGs through the MEDLINE database. The following data were extracted from each CPG and summarized: date of publication, country of the first author, type of organization that published the guideline, and whether and which category of interest-holder groups was engaged in the TCI CPGs.

Results
We identified 743 references from the database. The final results will be presented at the conference.

Discussion
Understanding the current status and gaps in interest-holder engagement in TCI CPGs not only helps improve the transparency and scientific rigor of TCI CPGs’ development but also facilitates the dissemination and implementation of TCI CPGs.

Background: Some question the usefulness of systematic reviews (SRs) when only one study addresses the relevant question. We faced this situation in an SR of metformin for treatment of non-serious COVID-19 infection undertaken to inform a WHO practice guideline.

Objective: To illustrate how SR authors can emphasize the value of their review when it includes only a single study addressing the question of interest.

Methods: We conducted an SR of randomized controlled trials (RCTs) addressing the effects of metformin on patient-important outcomes including long COVID.

Results: We identified three eligible RCTs, only one of which addressed the key outcome, long COVID. That RCT (1,126 patients) provided low certainty evidence that metformin may decrease long COVID (RR 0.6, 95% CI 0.4–0.9; RD 41 fewer per 1000, 95% CI 62 fewer – 10 fewer). The three trials provided evidence of little to no effect on other outcomes (certainty high to low). Reviewers of our submitted manuscript challenged the usefulness of our review given only a single trial addressed the key outcome. We noted i) that without the systematic search one would remain uncertain that there was indeed only a single RCT and ii) knowing that this was the only RCT allowed GRADE rating of certainty of evidence on the basis of that trial. The journal accepted the paper for publication.

Discussion: When it appears that only one relevant study for a key outcome is available, an SR can definitively ascertain that is the case and provide a GRADE certainty of evidence rating.

Background: Post COVID-19 condition (PCC), commonly referred to as long COVID, is a significant public health concern with wide-ranging impacts. Prevention strategies for PCC are critical in mitigating long-term complications. The Canadian Guidelines for Post COVID-19 Condition (CAN-PCC) were developed to provide evidence-based recommendations for PCC prevention.
Objective: To summarize and present key recommendations from the CAN-PCC guidelines for PCC prevention, including vaccination, ventilation, masking, and pharmaceutical interventions.
Methods: Guideline development followed the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach and adhered to AGREE II standards. The Evidence-to-Decision (EtD) framework was used to assess benefits, harms, values, costs, equity, acceptability, feasibility, and planetary health impacts of preventive interventions. Public and stakeholder consultations informed final recommendations.
Results: Key recommendations include: (1) additional doses of COVID-19 vaccines to reduce PCC risk (conditional recommendation, very low certainty), (2) optimizing indoor ventilation and considering air filtration for PCC prevention (conditional recommendation, low to very low certainty), (3) mask use in high-risk settings (conditional recommendation, very low certainty), and (4) pharmaceutical interventions such as metformin and nirmatrelvir-ritonavir for PCC prevention (conditional recommendation, low to very low certainty).
Discussion: While the recommendations provide actionable guidance, the evidence base remains limited, underscoring the need for further research on PCC prevention. Future studies should focus on high-risk populations, long-term effectiveness of interventions, and implementation feasibility. The CAN-PCC guidelines serve as a foundation for ongoing evaluation and adaptation in response to emerging evidence and evolving public health needs.

Background: Adapting guidelines can help avoiding duplication of efforts and the waste of resources compared to developing guidelines de novo.

Objective: To provide an overview of experiences and lessons learned from our efforts to adapt recommendations for a primary care guideline on functional abdominal pain in children.

Methods: We used the GRADE-ADOLOPMENT approach to adapt recommendations for (non-) pharmacological treatment for this guideline. The guideline panel selected a recent national secondary care guideline on functional abdominal pain (2022) as the source for adaptation, based on its scope, credibility, currency, feasibility, and applicability. We used the AMSTAR-2 tool to assess the quality of the systematic reviews.

Results: So far, we have adapted five recommendations. The quality of the systematic reviews included in the guideline was moderate. The rating of the quality of evidence required our attention due to missing justifications for downgrading. As a consequence, conclusions were rephrased, taking into account the minimal clinical importance differences established by the panel. In addition, we formulated new considerations for all recommendations according to the Evidence to Decision (EtD) framework. Three recommendations were changed from weak in favor to weak or strong against due to a lack of benefit. Two recommendations remained unchanged.

Discussion: Adapting guideline recommendations from secondary to primary care can be challenging, even within the same country, if different methods are used. Ideally, source guidelines should be developed using the GRADE approach, and considerations should be structured within an EtD framework.

Background
Antimicrobial resistance (AMR) is a growing threat to Latin America's public health, agricultural production and food security. The indiscriminate use of antibiotics in intensive livestock farming has accelerated the emergence of resistant microorganisms, compromising the effectiveness of treatments and increasing the risks of transmission of pathogens through the food chain.

Objective
To assess the burden of AMR associated with agricultural production in Latin America and their acknowledgement in national and regional guidelines.

Methods
This is an ongoing scoping review. Our inclusion criteria are studies addressing AMR in agricultural production in Latin America and national and regional clinical practice guidelines on antibiotic stewardship in Latin America. We searched the following databases: Medline, Global Health, Food Science Source, Lilacs, Web of Science, and study registers. We will collect data on the burden of AMR and investigate whether national or regional guidelines considered this in framing their recommendations.

Future prospects for project presentations
-Identify the strategies used in Latin America to combat AMR in agricultural production.
-Evaluate the impact of these measures on reducing the use of antibiotics and on food security.
-Analyze the barriers and facilitators in the implementation of health policies and agricultural practices.
-Identify evidence-based proposals for improvement to strengthen the fight against AMR and ensure safe food in the region.

Background
In King Abdulaziz University Hospital during the first quarter of 2023, 8% of Tonsillectomy cases were reported in ER with the chief complaint of post-tonsillectomy bleeding
Investigation was conducted to find the common cause was Non-compliance with nutritional guidelines which can be mitigated by proper health education and follow up.

Objective
Main Goal: “At the end of 2024 the percentage of the incidence of post tonsillectomy bleeding will decrease from 8% to 3% as benchmark internationally”

Methods
A workflow was created to ensure a structured approach to the Telenurse project. Discharge cards were generated for patients and families, detailing when to seek emergency medical attention if symptoms arise. Triage calling forms were designed to facilitate follow-up calls post-discharge. A pilot study was conducted to test the forms, and necessary modifications were made. ENT surgeons were involved in the project to provide specialized input. Training was provided to the team on the calling schedule, Staff compliance and key performance indicators (KPIs) were monitored monthly.

Results:
% of post Tonsillectomy Bleeding incidences were significantly decreased from 8% to 2%
Patient compliance with post-operative instruction increased
Patient engagement and patient centered care achieved
Patient experience enhanced (one mother said “I feel my child is very important person”

Discussion
The Telenurse project demonstrated the potential of structured telephonic follow-up in enhancing post-discharge care. Regular monitoring of staff compliance and KPIs contributed to the project's success. Future studies should explore the long-term impact of Telenurse on patient outcomes and its applicability to other specialties.

Background: Incorrect vascular access device (VAD) selection can cause complications in children. We aimed to standardize VAD selection using evidence-based interventions to improve outcomes.
Methods: A stepped wedge cluster randomised trial was conducted at a children’s hospital in Shanghai, China. Patients aged 28 days to 18 years requiring >24-hour (whether continuous or not) intravenous infusion were included. Electronic randomisation by the study statistician determined the sequence by which clusters crossed over from the control to the intervention group. Patients in the intervention group had VAD inserted according to guideline recommendations, while those in the control group used VAD selected based on common practice. Outcomes were appropriate VAD selection rate and infiltration incidence, analyzed by masked specialists using generalized estimating equations.
Results: From May to October 2022, 4652 VAD selection episodes in ten wards were analyzed. Compared with control group, the inappropriateness of VAD selection in the intervention group decreased by 26% (OR = 0.74, P= 0.003); the incidence of infiltration decreased by 36% (OR=0.64, P<0.001). The cost-effectiveness ratio for peripheral intravenous catheter infusion consumables indicated cost saving post-intervention.
Conclusions: Evidence-based VAD selection in hospitalized children reduces inappropriate selection rates, infiltration incidence, and infusion therapy costs.

Background: In 2024 ASCO piloted a new tool to assess the update needs for all published guidelines.
Objective: This project sought to achieve several goals: establish a uniform, evidence-based update assessment process; aid in identifying living guideline candidates; engage all panel members; utilize a quick input methodology; inform Guideline Advisory groups (GAGs) topic prioritization; and eliminate staff creation of individual update assessment forms.
Methods: Staff adapted features from several established tools, including Agile Technique, USPTF topic prioritization, and UpPriority. to create a focused prioritization tool centered on five core items: impact of outdated recommendations on safety, availability of new relevant evidence, context relevance and methodological applicability of the research questions, guideline user's interest, and impact on access to health care. For evaluation of each guideline using the adapted priority tool, a 7-question survey, estimated to take approximately 5 minutes, was distributed to guideline panels.
Results: The priority tool was used to assess 69 guidelines with 315 respondents. 80% found the tool easy or very easy to use, while only 1% encountered difficulty. Of 48 GAG members surveyed after prioritization, 96% (70% agreed, 26% strongly agreed) found the update assessments with the tool useful for topic prioritization.
Future prospects for project presentations: Overall, the staff, guideline panelists, and GAG members found the tool and process informative. However, areas for improvement were identified. These include providing an updated literature review to the panelists to enhance assessments, removing questions about update type, and exploring the feasibility of embedding recommendations directly into the survey.

Background: Sex and gender (S&G) are being increasingly recognized as important variables impacting the diagnosis, prognosis and management of several neurological disorders. Therefore, to ensure generalization and implementation of clinical practice guidelines (CPGs), S&G should be carefully pondered when issuing recommendations in the diagnosis and management of neurological disorders.
Objective: To review and appraise the integration of sex and gender variables in published CPGs from the European Academy of Neurology (EAN).
Methods: CPGs developed by the EAN and published from 2018 until June 2024 were evaluated by three independent reviewers, who checked their baseline characteristics, the use of S&G terminology, and the inclusion of S&G aspects in evidence analysis and issuing of recommendations. An adapted version of Hankivsky et al. checklist on gender-sensitive reporting was used for the latter, evaluating the inclusion of S&G variables in the research approach, PICO questions development, literature review, synthesis of evidence, issuing of recommendations, and implementation. CPG Task force Co-chairs (two per CPG) were invited to answer questions which the authors considered to require specialist expertise to be answered.
Future prospects for project presentations: Sex and gender and other diversity variables need to be considered from the early stages of the CPGs Development of the EAN. However, although the CPG Task force Co-chairs acknowledge the impact of S&G variables in recommendations, their implementation remains a challenge.

Background: As interest in clinical practice guidelines (CPGs) grows, patient-version guidelines are being developed internationally to improve patient comprehension. These guidelines translate clinical recommendations into accessible, patient-friendly language, aiding decision-making and fostering trust between patients and healthcare professionals. In South Korea, patient-version guidelines are not yet widely recognized, highlighting the need for further research and structured development approaches.

Methods:To enhance patient engagement and comprehension, a patient-version guideline for mild cognitive impairment (MCI) was developed by simplifying medical language. The process involved selecting content from CPG recommendations, refining language using pictograms and improved formatting, conducting document reviews with the NECA public participation panel, incorporating face-to-face expert feedback, and finalizing revisions based on suggestions. Plans were made for its dissemination to relevant organizations.

Results: The guideline for patients was reviewed by the NECA panel from December 6-11, 2024, receiving an average score above 7 on a 10-point scale for clarity, usability, and applicability. Participants found it informative and useful for patients and caregivers. While some requested additional details, others preferred conciseness. During the guideline presentation session, experts acknowledged its limitations as a supplementary tool for clinical practice guidelines while emphasizing the importance of patient version guideline development. It was also acknowledged as the first formally developed patient-version guideline in Korea, marking a significant milestone.

Conclusion: Early identification of the target audience and direct involvement of patients and the public are crucial in developing patient-version guidelines. Future efforts should reference practical cases to enhance patient understanding and engagement in disease management.