Background
The care of palliative patients involves various professionals, including medical specialists, general practitioners, nurses, spiritual caregivers, and paramedics. This diversity necessitates multidisciplinary guidelines to ensure inclusivity and practical applicability. The Dutch institute for Palliative Care (PZNL) developed a stepwise method to engage all relevant professionals in guideline development, ensuring alignment with their expertise and practices.

Objective
To describe and evaluate a structured, multidisciplinary approach to developing palliative care guidelines that reflect the knowledge and needs of all care providers and patient populations.

Methods
A six-step method was applied, involving: (1) topic selection by representatives from professional associations, (2) creation of a multidisciplinary working group including patient representatives, (3) identification of key issues via surveys distributed across professions, (4) iterative feedback and refinement, (5) authorization by professional societies, and (6) dissemination and implementation through guideline platforms and newsletters.

Results
Surveys for four recent guidelines involved 30% nurses, 35% physicians (11% general practitioners), 17% physician assistants, 6% spiritual caregivers, and 8% paramedics.

Across the last eight guidelines, working groups included nurses (100%), internists (88%), geriatricians (88%), general practitioners (75%), and dieticians (50%), alongside patient input.

All steps ensured broad representation and alignment with professional practices.

Discussion
The stepwise method successfully integrates diverse perspectives, resulting in widely accepted and practical guidelines for palliative care. Future research should focus on assessing long-term outcomes of guideline implementation.

Background
The international development sector (IDS) could benefit from standardization of practices to develop evidence-based guidelines that best fit this context.

Objective
To adapt guideline development methods to the IDS to enhance the transparency, rigor and reproducibility of Evidence Informed Decision-Making.

Methods
We will conduct a modified Delphi to explore the perspectives of interest holders we regularly work with on the value of guidelines in the IDS. We will first provide them with a training manual on guideline development methods. Then we will share a draft extension of the GIN-McMaster Checklist for IDS and ask them for their agreement on the proposed items using an online survey. We will refine and conduct a consensus meeting to discuss any items that received less than 80% agreement. Then we will draft a set of signaling questions to help make judgements for the criteria of the Evidence to Decision framework (EtD). We will reach out to the interest holders for their input on the EtD criteria and the signaling questions, and ask them to assess the likelihood of them applying it in their practice, and refine accordingly.

Results
We will present the draft extension for the GIN McMaster checklist in the IDS, summarize the perspectives of interest holders, and the modified version of the EtD. We will present the distribution of scores and show the range of responses.

Discussion
The findings will be used to pilot a guideline development project in key priority areas for the International Initiative for Impact Evaluation (3ie)’s partners.

Background
Teleconsultation is a vital tool for improving healthcare access in Colombia, especially in underserved regions. However, its implementation faces persistent challenges, including financial reimbursement challenges and weak integration among key stakeholders. A fragmented regulatory environment and misaligned incentives between insurers, providers, and policymakers further complicate adoption. Addressing these gaps requires a multi-sectoral, collaborative approach.

Objective
This study examines how systemic fragmentation affects teleconsultation in Colombia, and proposes strategies for multi-sector integration.

Methods
A qualitative abductive analysis was conducted based on 27 interviews with key stakeholders, including healthcare providers, policymakers, and patient advocacy representatives. Thematic coding identified patterns related to structural challenges and actor coordination. Findings informed a conceptual model outlining strategies to enhance teleconsultation adoption.

Results

In Colombia, despite the national teleconsultation legal framework mandating government reimbursement, delayed and inconsistent financial payments discourage providers from offering these services. Misalignment between insurers, regulators, and healthcare providers results in fragmented service delivery, while limited institutional support and unclear payment models further hinder adoption. Stakeholders emphasised the urgency of standardised policies and targeted incentives to ensure sustainability.

Discussion

Strengthening teleconsultation requires coordinated policies aligning health, digital infrastructure, and financial frameworks. Strategies like targeted provider incentives, cross-sector partnerships, and patient-centred reimbursement models are critical for sustainable integration. A health-in-all-policies approach, leveraging collaboration across sectors like education and technology, can drive effective telehealth adoption in Colombia. Enhancing governance structures and fostering intersectoral partnerships are essential to embedding teleconsultation into routine healthcare delivery.

Background
The guideline 'Oral problems in the palliative phase' was developed by a multidisciplinary working group, using an evidence-based approach. Professionals and patients actively participate in the guidelinedevelopment process to ensure that recommendations align with their perspective
Multidisciplinary collaboration is also essential in the development of materials for guidelines.
Successful implementation of guidelines requires tailored dissemination strategies that effectively reach diverse target groups including healthcare professionals, patients and family.

Objective
We explore whether simultaneously developing innovative dissemination materials has an effect on guideline implementation.

Methods
A multidisciplinary working group, collaborated to develop dissemination materials. Various formats were selected to enhance accessibility and usability:
To evaluate the impact of these dissemination strategies, a mixed-methods approach was employed, combining web analytics.

Results
We have established successful collaborations with several parties. This resulted in the following developed products or that are under development such as:
• An AI-generated video highlighting key updates for healthcare professionals;
• Information for patients and family on websites www.overpalliatievezorg.nl and www.Thuisarts.nl;
• Integration of results in existing apps and formulary for health care professionals (app PalliArts and the Palliative Formulary).
Figures and success factors will be shared during the conference.

Conclusion
Simultaneously developing innovative dissemination materials improved guideline accessibility. Multidisciplinary collaboration is essential for effective dissemination and implementation of palliative care guidelines.

Future prospects for project presentation
Future developments, such as AI-driven summaries, interactive e-learnings and real-time decision support tools, will focus on enhancing accessibility, engagement, and integration of guideline materials into daily practice and support healthcare professionals.

Background: Systematic reviews play a crucial role in clinical practice, serving as the foundation for guidelines and practical recommendations. However, creating new guidelines demands substantial time and resources. An efficient alternative is adapting existing guidelines for use in a different jurisdiction, a process that is faster and more resource-effective compared to starting from scratch. Traditionally, adaptation methods are carried out solely by the adapting committee or organization. NICE, however, enhances this process through contextualization, incorporating capability-building initiatives to support organizations in locally adapting guidelines.

Objective: To explain the NICE contextualization process, highlighting the support and guidance provided, and illustrating the process through various scenarios.

Format:
Interactive Workshop: The session starts with a brief presentation of the NICE contextualization process (20% of the time), followed by an engaging practical exercise (50% of the time). This is complemented by a facilitator-led discussion with participants (25% of the time) and concludes with a summary (5% of the time).

Practical Exercise: Participants will work in smaller groups to explore curated scenarios. They will adapt recommendations to different contexts and document the changes made, along with the reasoning behind these modifications.

Discussion: Facilitators will encourage participants to reflect on their experiences with the NICE contextualization process, discuss potential enhancements to the tools, and compare this approach with others used in their own settings.

Summary and Conclusion: The moderator will lead a collaborative effort between facilitators and participants to develop a concise summary of actionable outcomes.

Background: Quantitative analysis of national data on congestive heart failure (CHF) indicates that direct CHF-related healthcare costs are increasing by 7.9% annually, while Singapore’s 2020 CHF-related readmission rates (20%) are similar to the lowest-performing OECD country (17%). The Agency for Care Effectiveness (ACE) conducted a situational analysis of the current disease burden, practices, healthcare utilisation, and care pathway to inform next steps, as part of the overall Appropriate and Value Based Care (AVBC) initiative.

Objective: To identify areas of low-value care and propose priorities for a national CHF strategy aligned with AVBC principles and guideline-directed standards of care.

Methods: ACE conducted a situational analysis including: (a) qualitative interviews with 3 primary care physicians and 5 cardiologists to identify systemic gaps and barriers, and (b) systematic searches of guidelines and literature to identify potential practice gaps from guideline-directed standards.

Results: Four high-quality international guidelines (assessed by AGREE II) were appraised. Comparing Singapore’s care landscape with guideline standards and integrating interview insights, six priorities emerged: (a) strengthening CHF prevention in primary care, (b) expanding primary care’s role in chronic CHF management, (c) improving care transitions to reduce readmissions, (d) expanding resources to manage decompensations at home, (e) developing end-of-life care strategies, and (f) establishing person-centred performance framework prioritizing patient-reported outcomes.

Discussion for scientific abstracts: As next steps, a multidisciplinary workgroup will co-develop AVBC recommendations with ACE, incorporating patient voices, to inform a national CHF strategy addressing low-value care and identified priorities.

Background

The Norwegian Directorate of Health is mandated to develop and maintain national clinical guidelines. These guidelines provide normative recommendations for healthcare providers on various aspects of healthcare services delivery. This is to ensure high quality and equitable healthcare services for all Norwegians. Research has shown that health of individuals is affected by their socioeconomical status. Factors affecting the socioeconomical status of individuals such as education, childcare, employment or other social welfare issues are affected by various services delivered through other directorates or organizations under the Norwegian government.
We present a case where The Norwegian Directorate of Health in collaboration with The Norwegian Directorate for Children, Adolescents and Families has developed a new national guideline for interdisciplinary health assessment in the context of child protection services in Norway.

Objectives

The objective of the new guidelines is to facilitate interdisciplinary health assessment in child protection services in an equitable manner for all Norwegians. The recommendations are intended to help ensure that child protection services receive adequate information about children health and support needs, to reduce the risk of unintended transfers and wrongful placements.

Methods

We follow an evidence-based approach in developing national guidelines, where knowledge from academic literature, clinical experience and user feedback is systematically assessed in the development process. Due to a limited body of research addressing this area, we drew more on professional experience and user feedback.

Results

This is a work in progress and the project team is currently receiving and evaluating external feedback.

Background
WHO guidelines development are a collaborative effort created to provide support to member states in the delivery of optimal healthcare. This is largely dependent on rigorous evidence synthesis and applicability to the local context of each region.

Objective
This project aimed to synthesize available research on to support the World Health Organization (WHO) guideline update on pediatric fluid and blood management in acute illness.

Methods
A comprehensive search was conducted in PubMed, EMBASE, CENTRAL, and CINAHL until August 2023. Two reviewers independently screened titles & abstracts and full texts according to prespecified eligibility criteria. Data was extracted and quantitatively pooled. Risk of bias was assessed using either Cochrane risk of bias 2 (RoB) or the Risk of bias in nonrandomized studies of intervention (ROBINS-I). We assessed the certainty of evidence (CoE) using the GRADE approach.

Results
Forty-four studies informed our analyses. Eighteen (40%) were from high income countries (HICs) and 26 (60%) were from low- and middle- income countries (LMICs). In children unable to tolerate enteral intake, isotonic fluids reduced hyponatremia risk versus hypotonic fluids (RR:0.34, 95% CI:0.25 to 0.46, High CoE). In children with circulatory impairment, bolus administration increased 48-hour mortality (RR:1.45, 95% CI:1.13 to 1.86, Moderate CoE).

Discussion for scientific abstracts
The largest trial, informing the guideline on resuscitation with fluid boluses, posed issues with generalizability to HICs with facilities for fluid overload monitoring and other regional patient-specific characteristics. An innovative approach to interpreting and implementing evidence from one resource setting to another should be prioritized.

Background
Health equity is critical to inform clinical practice guidelines and policy. Integration of concepts of health equity into the decision-making of recommendations ensure applicability to a diverse population. The American Academy of Pediatrics (AAP) plans to update previous policies for the diagnosis and management of children with autism spectrum disorder with a more race-conscious approach.

Objectives
This study conducted an umbrella review of systematic reviews on race- and ethnicity-related factors that impact pediatric ASD diagnosis and management to inform an update of AAP policy on ASD care.

Methods
A comprehensive search was conducted in PubMed, EMBASE and Cochrane library from inception to October 2025 for published systematic reviews reporting on ASD prevalence, diagnostic tools, interventions and outcomes within the context of race and ethnicity. Two reviewers independently screened studies and extracted data. Reviewers assessed the quality of using the Assessment of Multiple Systematic Reviews (AMSTAR 2) tool. PROGRESS-Plus framework was employed to identify other equity factors related to race & ethnicity.

Results
At the data extraction stage, we have identified 80 published systematic reviews. However, we anticipate variations in the methodological rigor that indicate an opportunity for more robust methods in evidence synthesis, especially relating to equity.

Discussion for scientific abstracts
This umbrella review will facilitate an improvement in how racial equity is approached in the design, conduct, synthesis and interpretation of ASD research. If an underrepresentation of ethnic groups is found, it will be a call for future researchers to actively engage the diversity of persons with ASD.

Background:
Screening programs for breast, cervical and colorectal cancer are crucial for early detection of precancerous lesions. Ensuring equitable access, public acceptability, and implementation feasibility remains challenging. Evidence to Decision (EtD) frameworks address these factors, but communicating subjective and indirect evidence presents challenges.

Objective:
We aimed to investigate strategies to communicate evidence on equity, acceptability, and feasibility in EtDs to expert panels.

Methods:
We conducted overviews of systematic reviews (SR) to examine the available evidence on equity, acceptability, and feasibility of cancer screening. When no direct evidence was found for some questions, a stepwise approach was used to find additional evidence. If there was still a lack of evidence after additional searches, we attempted to communicate the generalized findings in a way that supported expert panel decision-making.

Results:
The initial overview searches informed EtDs for 18 PICOs but found no direct evidence. Lacking direct evidence on equity, acceptability, and feasibility led to reliance on general, often heterogeneous findings. Expert panels faced difficulties in contextualizing such evidence, highlighting a critical gap in existing EtD methodologies. The integration of simple language summaries was a promising approach, but further refinements are needed.

Discussion:
Overviews of systematic reviews provide a baseline summary of existing research on general acceptability, equity and feasibility of cancer screening. However, they can lack detail when examining outcomes for specific populations or interventions. Enhancing clarity in evidence interpretation, developing better strategies for summarizing indirect evidence, and fostering panel understanding are crucial next steps to better inform decision-making.

Background
Multimorbidity is becoming increasingly prevalent in low- and lower-middle-income countries (LMICs). This is burdensome due to limited resources, social disparities, and conditions developing at younger ages compared to in high-income countries (HICs). Previous reviews of guidelines have focused on HICs and it is currently unclear what informs multimorbidity care in LMICs.
Objective
To conduct a scoping review to identify multimorbidity management guidelines and policy documents for LMICs.
Methods
Clinicians and patients with multiple long-term conditions formed an advisory group contributing to study design and interpretation of findings. A protocol was established a priori following JBI methodology and informed by an evidence gap map.
Using a comprehensive search strategy, bibliographic databases (e.g. Medline, Embase, CINAHL, Cochrane Library) were searched in February 2025 to identify multimorbidity-related guidelines and policy documents. African Journals Online and GIN databases were searched manually. Using predefined criteria, titles and abstracts have been screened, and full text screening is in progress. The AGREE and RIGHT tools will be used to assess the quality of included guidelines and a pre-piloted data extraction form will facilitate charting. Contextual understanding of organisation of care and research gaps will be identified and mapped.
Results
The search resulted in 31,673 references, of which 70 have been included following title and abstract screening. Full evidence summaries and results will be presented at the GIN conference.
Discussion
This summary of evidence will provide insight for future multimorbidity guideline research and capacity development, which could help to support management and reduce disease burden.

Background: The Public Consultation (PC) of Clinical Practice Guidelines (CPG) allows capturing patients' values and preferences, as well as considerations regarding technologies and implementation aspects in the evaluation process by the National Committee for Health Technology Incorporation (Conitec).
Objectives: To evaluate the profile of contributions and participants in PC on CPG in 2024.
Methods* Data from all CPG PC in 2024 were collected. Characteristics of the participants and contributions were summarized in frequencies.
Results: Thirty CPG were submitted to PC: of which 70% addressed rare diseases, 16.7% oncology disease, 10% chronic non-communicable diseases and 3.3% chronic communicable diseases. In total, 3,545 contributions were received. The mucopolysaccharidosis type 1 CPG received no contributions. On the other hand, multiple sclerosis CPG received 792 contributions. Most of the participation was from family members, friends, or patient caregivers (32.4%), followed by healthcare professionals (29.4%) and patients (24.3%). The participation of companies, public institutions or pharmaceutical industry represented around 5% of the contributions. Individual participants identified themselves as of white color/ethnicity (65.6%), 25-to-39 years (46.5%) and residing in the south region of Brazil (48.4%). Friends, colleagues, or coworkers (42.4%) and social networks (25.8%) were also the main sources of knowledge in the PC.
Conclusions: Although the profile of participants is similar in CP, the number of contributions varies between CPG, with rare diseases standing out from other topics. Monitoring contributions and the profile of participants can help Conitec understand the dynamics of society's participation in the process and promote improvement strategies.

Background
Korea's National Immunization Program (NIP) has a long-standing history of providing free essential vaccinations and maintaining high vaccination rates. The program currently covers 19 infectious diseases, continuously expanding its scope. However, there is a need for evidence-based policy decisions to ensure program sustainability.
Objective
To establish a system for evidence-based recommendations and effectiveness evaluations for Korea's NIP Committee, ensuring scientifically informed policy-making and NIP operations.

Methods
The Korea Disease Control and Prevention Agency (KDCA) and NECA's GRADE Center are collaborating to implement a framework for systematic, evidence-based effectiveness evaluations. A new evidence review procedure for introducing vaccines is being established, considering disease and vaccine characteristics, resource allocation efficiency, and vaccination acceptability. Effectiveness evaluations for existing vaccines (e.g., pneumococcal, HPV) are conducted using cohorts linking vaccination history, National Health Insurance Service claims data, and national health screening data.
Results
Evidence evaluation system was established for The NIP Committee's 9 subcommittee through analyzing the latest research on vaccines, diseases, and epidemiology, along with changes in vaccination guidelines. Systematic reviews are being conducted as needed for public recommendation. National surveys on public perception of immunization are ongoing.

Discussion for scientific abstracts
This approach is expected to contribute to evidence-based recommendations tailored to Korea's needs, based on the latest scientific evidence. The establishment of a continuous vaccine effectiveness evaluation system will provide crucial evidence for the NIP's effective operation. This systematic, evidence-based approach will enhance the program's credibility and effectiveness, potentially improving public health outcomes through optimized vaccination strategies.

Background
Participation in guideline panels requires specific knowledge and skills. To help nurses, clinical nursing assistants, and nurse specialists effectively represent their professional groups, the Dutch professional association for nursing (V&VN) organizes guideline training multiple times a year. However, due to the diverse backgrounds and varying levels of academic knowledge among healthcare professionals, the training may not always meet their needs.

Objective
This project aimed to identify the knowledge and skills needed by nursing guideline panel members and adjust the training accordingly.

Methods
Ten interviews were conducted with former guideline panel members, chairs, and V&VN advisors. Based on the interview results, a questionnaire was developed and distributed to 302 former guideline panel members and chairs. The responses were summarized to guide adjustments to the current training.

Results
Five former guideline panel members, two former chairs, and three V&VN advisors were interviewed in 2024. A total of 91 individuals completed the questionnaire. Key challenges identified were: differences in knowledge levels regarding guideline methodology, preferences for in-person versus online training, and insufficient coverage of topics like representing one’s professional group and managing conflicts of interests.

Discussion
In the first half of 2025, the findings will be used to improve the training for panel members in nursing guidelines, ensuring it better meets the needs of nurses, clinical nurse assistents, and nurse specialists involved in guideline development.

Background
Autism spectrum Disorder (ASD) is a neurodevelopmental disorder with a crucial need for early diagnosis in children to optimize developmental outcomes. Therefore, it is important for guideline developers to create methodologically rigorous recommendations which address factors that may lead to disparities in diagnosis and management.

Objectives
The objective of this study is to conduct an equity review and critical appraisal of professional and government sponsored pediatric ASD diagnosis and management guideline documents.

Methods
A comprehensive search was conducted in PubMed and EMBASE until August 2024. Professional and governmental websites of organizations which produce pediatric focused health policy documents were also searched for relevant documents. Data from eligible studies were extracted to a spreadsheet. Equity factors were assessed and extracted using the PROGRESS-Plus framework. The quality of each eligible document was assessed using the Appraisal of Guideline Research and Evaluation Second Edition (AGREE-II) tool.

Results
The 24 included documents addressed at least one PROGRESS-Plus equity characteristic. The Australian, New Zealand, and National Institute for Health and Care Excellence (NICE) guidelines which had the highest AGREE-II scores translated their equity considerations to specific recommendations for each subgroup of ASD persons. In contrast, other guidelines mainly presented background information.

Discussion for scientific abstracts
This appraisal revealed varying degrees of methodological rigor organizations incorporate in the development guidelines. Future guidelines should prioritize a more comprehensive approach to equity by providing recommendations or actionable statements to aid the practitioner in addressing systemic barriers that lead to disparities and inequity in ASD Diagnosis and management.

Background: Human brucellosis is a re-emerging zoonosis with significant public health importance, requiring comprehensive approaches for proper management. 

Objective: To describe the process of developing the Human Brucellosis Guideline for the Brazilian public health system. 

Methods: This study presents a case report following the requirements of Methodological Guidelines to the development of clinical guidelines from the Brazilian Ministry of Health (MoH).

Results: The initial stage of the process focused on defining the guideline's scope, where dialogue among stakeholders played a critical role in delineating and reaching a consensus on its objectives. A major challenge was engaging social participation, which was addressed through public calls aimed to encourage wider participation. During the development phase, two major challenges were the limited number of primary studies on brucellosis and the need to conduct systematic reviews of existing evidence. Five systematic reviews were conducted, which informed the discussions of evidence panels convened to address key questions and support the incorporation of a new drug into the Brazilian Unified Health System (SUS). This process included evidence assessment, regulatory compliance, and policy alignment. The active participation of stakeholders in this stage was fundamental, contributing to a comprehensive, scientifically robust guideline that enhances national healthcare strategies. In addition, dissemination strategies were designed to integrate the guideline into broader public health efforts, maximizing its utility and impact. 

Discussion: By applying systematic and evidence-based standards, it facilitates the development of policies that transcend traditional healthcare boundaries, enabling timely, informed, and effective decision-making frameworks to improve health outcomes.

Patient and public involvement (PPI) has become a cornerstone of ethical, patient-centered health research and healthcare delivery, enhancing research relevance, methodological rigor, and societal impact. Globally, regulatory frameworks increasingly mandate PPI integration across research prioritization, study design, and policy development. However, despite this progress, gaps in implementation, impact assessment, and sustainability continue to undermine meaningful engagement. This narrative review explores a decade of evidence to examine PPI’s global trajectory, applications, impact assessment, and unresolved challenges. While various norms provide a foundation for PPI implementation, inconsistencies remain. In clinical trials, although 40% of studies incorporate PPI, researchers often limit engagement to the early design phases, rarely extending it to data analysis or dissemination. PPI in systematic reviews and clinical guidelines exhibit similar constraints, as tokenistic participation and inadequate reporting often define their PPI integration. Qualitative evidence highlights PPI’s role in improving recruitment, fostering trust, and enhancing intervention relevance, yet rigorous quantitative validation remains scarce, with current evaluation frameworks lacking standardized metrics. Key barriers include superficial engagement, weak institutional commitment, the absence of validated assessment tools, and insufficient funding for sustained involvement. Translational and preclinical research lags further behind, where researchers often limit PPI to brief consultations rather than substantive contributions. Future priorities should focus on developing robust quantitative impact assessment tools, refining comprehensive guidelines with clear justifications for PPI, and equipping researchers with concrete strategies for meaningful implementation. Addressing these challenges is crucial to ensuring that PPI drives substantive improvements in health research and healthcare rather than remaining a procedural requirement.